Ok who did this


@minouye271 Challenge me that this association is not among the strongest you'll see in a month. It's significant & meaningful.


@darioT_ @minouye271 So ... people ... get older? 🤯


@almosnow @minouye271 Apparently, there is a linear correlation, that is strongly associated with time. Evidence show that people over 40y are overall older than people aged 18-35y (P=0.0000569), representing a clinically meaningful difference with immediate implications in an area of high unmet need.


@darioT_ @almosnow @minouye271 Older people, on average, are older than average younger one! Amazing!


@genereporter @almosnow @minouye271 🚨 I agree: the evidence is #revolutionary 💣💣💣💥 Shall we write a review to emphasize and spread better the message? 🎉


@genereporter @almosnow @minouye271 I also have an entire #RWE case series that can work. I offer: 🥇10.8K individuals 🥈"Strong" associations 3️⃣VERY significant P-values 🍀nice KM ('time to 45y') 5️⃣ adjustment for relevant confounders: initials of name, N of previous cars.


@darioT_ @genereporter @almosnow @minouye271 I think lots of you are now assuming causation from correlation and we just can’t do that. It’s not right to assume that people getting older is making them older


@hisotalus @genereporter @almosnow @minouye271 However, that's plausible. (My) Plausibility gives credit to my assumption 😌😌😌


@darioT_ @genereporter @almosnow @minouye271 I personally think it’s the other way around - people getting younger is making people younger - but it’s possible that some third factor causes both age and age to increase /decrease. What would happen to this effect if they controlled for body weight or time passed since birth?


@hisotalus @genereporter @almosnow @minouye271 Past highly-biased series CLEARLY show that weight is insignificant and has no prognostic role. 3️⃣ real life series from people I know in my village all converge toward the same conclusion. There's another one, independent, that says differently but we're bullying on them 👊


@darioT_ @hisotalus @genereporter @almosnow @minouye271 Except gravity makes time slow down. Where might you experience higher weight? In a strong gravity field. 🤪


@wtspman @hisotalus @genereporter @almosnow @minouye271 I guess gravity is one of those variables likely to affect.


@darioT_ @wtspman @hisotalus @almosnow @minouye271 Sandra Bullock may be an outlier then.


@genereporter @wtspman @hisotalus @almosnow @minouye271 So problematic to manage outliers...


@darioT_ @genereporter @wtspman @hisotalus @almosnow @minouye271 Best thread today by miles.


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